西班牙Certest空腸彎曲桿菌重組外膜蛋白

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西班牙Certest空腸彎曲桿菌重組外膜蛋白

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與大多數(shù)人來源的“不朽”細胞(包括從腫瘤組織中獲得細胞)不同，這些新創(chuàng)建的不朽細胞具有正常的基因組。伯克利實驗室生命科學部科學家Martha Stampfer說：這些細胞可能有助于開辟新的策略來對抗癌癥。細胞永生化也可以是一個重要的治療靶標。
Stampfer補充道：現(xiàn)在我們可以獲得攜帶正?；蚪M的無限增殖的人類抗原抗體上皮細胞，去探索細胞永生化的背后分子機制，我們也可以開始思考如何針對細胞永生化這一過程，防止或逆轉癌癥的發(fā)展。
干細胞(Stem Cells)被稱作人體組織細胞的自然蓄水池，擁有自我復制(自更新)和隨時分化成其它更專業(yè)化功能細胞的*能力，如此成為醫(yī)學科技人員治療一系列疾病和人體組織損傷強有力的技術工具。然而干細胞研究并非沒有爭論，特別是胚胎干細胞研究，已在科技界以及更廣泛的社會各界引發(fā)爭議。
歐盟干細胞研究正處于勃勃生機的“開花結果”階段，盡管部分研究仍處于前沿的科學探索，但系列的主要研究活動已轉向應用研究或商業(yè)化應用開發(fā)前期。例如，通過觀察控制干細胞，歐盟科技人員已實現(xiàn)準確的干細胞專業(yè)化功能開發(fā)，可廣泛應用于治療重大疾病，如癌癥或細胞異常分裂與分化引發(fā)的先天性缺陷疾病。
目前，歐盟干細胞研究的商業(yè)化應用，主要針對人體受損細胞替代的疾病治療，包括大面積燒傷、白血病患者的血液系統(tǒng)修復和心血管系統(tǒng)醫(yī)療。正在開展干細胞直接分化成專業(yè)化功能細胞類型，進行治療包括帕金森疾病(Parkinson’s)、中風、心臟病和糖尿病在內(nèi)的臨床試驗。
歐盟第七研發(fā)框架計劃(FP7)和歐盟2020地平線(Horizon 2020)，是歐盟層面資助干細胞研究的zui主要平臺。目前資助的干細胞研究研發(fā)創(chuàng)新項目主要包括：應用干細胞開發(fā)神經(jīng)功能化細胞;干細胞修復中風損傷細胞;干細胞應用技術、工具、標準開發(fā)及社會文化普及;干細胞毒理學篩選技術;干細胞融合技術治療帕金森疾病;和負責任的干細胞科研與創(chuàng)新等等。
據(jù)來自東芬蘭大學的一項研究證實：SIP1蛋白在咽部鱗狀細胞癌腫瘤中的表達往往預示一種晚期的腫瘤分期，一種復發(fā)高危及預后不良。
基于該結果提示，SIP1或是可用于臨床使用的潛在預后因素，幫助預測哪些患者有更侵襲性的腫瘤行為，以確定是否需要更密集的治療。
雖然咽部鱗狀細胞癌(pharyngeal squamous Cell carcinoma, PSCC)是一個比較罕見的疾病，但在過去的三十年它的發(fā)病率一直在增加。
在所有頭頸部鱗狀細胞癌中，咽部鱗狀細胞癌是預后zui差的一種。盡管多式療法聯(lián)用的可用性，但預后并沒有得到任何顯著改善。

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【公司名稱】 廣州健侖生物科技有限公司
【市場部】    楊永漢

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【騰訊  】 2042552662
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號二期2幢101-103室

Unlike most immortal cells, including those obtained from tumor tissue, these newly created immortalized cells have a normal genome. Martha Stampfer, a Berkeley Lab Life Science scientist, said these cells may help open up new strategies to fight cancer. Immortalization of cells can also be an important therapeutic target.
Stampfer added: Now we can get the unlimited proliferation of human antigen-antibody epithelial cells carrying the normal genome to explore the molecular mechanism behind the immortalization of cells, we can also start thinking about how to deal with cell immortalization to prevent or reverse the cancer development of.
Stem Cells, known as natural reservoirs of human tissue cells, have the unique ability to self-replicate (self-renew) and readily differentiate into other more specialized functional cells, thus becoming a medical technologist for the treatment of a range of diseases and human tissues Damage powerful technical tools. However, stem cell research is not without controversy. In particular, research on embryonic stem cells has caused controversy in the scientific and technological community as well as in the wider community.
The EU stem cell research is in the midst of an "inflorescence" stage of vitality. Although some of the studies are still at the cutting edge of scientific exploration, the major research activities of the series have shifted to the early stages of applied research or commercial application development. For example, through the observation and control of stem cells, EU scientists and technologists have developed accurate stem cell specialized functions and are widely used in the treatment of major diseases such as cancer or congenital defects caused by abnormal cell division and differentiation.
Currently, the commercialization of EU stem cell research is focused on the treatment of diseases that are replaced by damaged cells in humans, including extensive burns, blood system repair in patients with leukemia, and cardiovascular system medicine. Direct differentiation of stem cells into specialized functional cell types is underway for the treatment of clinical trials including Parkinson's, stroke, heart disease and diabetes.
The EU's FP7 and EU 2020 Horizon 2020 are the main platforms for funding stem cell research at the EU level. Stem cell research and development currently funded innovative projects include: the application of stem cells to develop neurofunctional cells; stem cells repair stroke injury cells; stem cell technology, tools, standard development and social and cultural popularization; stem cell toxicology screening technology; stem cell fusion technology for Parkinson Disease; and responsible stem cell research and innovation and more.
According to a study from the University of Eastern Finland, the expression of SIP1 protein in pharyngeal squamous cell carcinoma tumors often indicates a late stage of the tumor, a high recurrence rate and a poor prognosis.
Based on this result, SIP1 is either a potential prognostic factor for clinical use, helping to predict which patients have more aggressive tumor behavior to determine if more intensive treatment is needed.
Although pharyngeal squamous cell carcinoma (PSCC) is a relatively rare disease, its incidence has been increasing over the past three decades.
In all head and neck squamous cell carcinoma, pharyngeal squamous cell carcinoma is the worst prognosis. Despite the availability of multi-modality therapy, the prognosis has not seen any significant improvement.