Anti-CCM2抗體,腦海綿狀血管畸形蛋白2抗體科研產(chǎn)品介紹：
Cerebral cavernous malformation (CCM) is an autosomal dominant or sporadic neurovascular disease marked by vascular anomalies located mostly in the central nervous system that can cause stroke, seizures, cerebral hemorrhages, headaches and focal neurologic deficits. CCM is caused by mutations in one of three genes: CCM1, CCM2 or CCM3. CCM1 encodes the protein KRIT1, CCM2 encodes the protein Malcavernin and CCM3 shares its name with the protein it encodes. Malcavernin, also designated cerebral cavernous malformations 2 protein, is a scffolding protein for MEK kinase-3. Like KRIT1, Malcavernin is expresed in a variety of human organs including the arterial vascular endothelium, pyramidal neurons, astrocytes and their foot processes. In addition, Malcavernin is expressed in various epithelial cells that are required for the formation of the blood-organ barrier. Malcavernin is localized to the cytoplasm but is known to shuttle to and from the nucleus. Due to its lack of a nuclear export signal or nuclear localization signal, it is believed that Malcavernin accomplishes this shuttling via an attachment to KRIT1, which contains a nuclear localization signal. Two isoforms exist for Malcavernin. Isoform 1 represents the full length protein while isoform 2 contains an alternative four amino acid sequence rather than the first 10 residues of isoform 1.
與“Anti-CCM2抗體,腦海綿狀血管畸形蛋白2抗體科研"有關(guān)的產(chǎn)品：
突觸結(jié)合蛋白10抗體 Anti-Synaptotagmin X
肌細胞增強因子2抗體 Anti-MEF2A
軸索過度生長抑制因子B受體抗體 Anti-NGBR/Nogo B receptor
多藥耐藥蛋白/P-糖蛋白抗體(C端) Anti-MDR1/p-GP/CD243 (C-terminus)
雙微體2癌基因抗體 Anti-MDM2
卵黃狀黃斑病蛋白4抗體 Anti-Bestrophin 4
膜相關(guān)鳥苷酸激酶1抗體 Anti-MAGI1/IRSP58
髓樣細胞白血病-1抗體 Anti-Mcl1/BCL2L3
巨噬細胞克隆刺激因子抗體 Anti-MCSF/M-CSF
卵黃狀黃斑病蛋白3抗體 Anti-Bestrophin 3
產(chǎn)品詳情：
產(chǎn)品編號：HRK-11817R
產(chǎn)品規(guī)格: 0.1ml/0.2ml
產(chǎn)品別名：Malcavernin; C7orf22; Ccm2; CCM2_HUMAN; Cerebral cavernous malformation 2; Cerebral cavernous malformations 2 protein; Malcavernin; MGC4067; MGC4607; MGC74868; PP10187
產(chǎn)品價格：詢價(電詢或客服)
產(chǎn)品用途：科研實驗
貯 存： 貯存于-20℃.
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