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華瑞科研網(wǎng)-ELISA試劑盒
華瑞科研網(wǎng)-ELISA試劑盒
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更新時間：2018-04-08 21:38:51瀏覽次數(shù)：177次
聯(lián)系我時，請告知來自 智慧城市網(wǎng)“Anti-phospho-CDKN2A（Ser8）,磷酸化抑癌基因p16抗體科研“我公司擁有*的細(xì)胞服務(wù)技術(shù)，*的儀器設(shè)備和專業(yè)的ELISA檢測試劑盒、生物索標(biāo)記、熒光索標(biāo)記、酶標(biāo)記等，廣泛用于多種分析研究與技術(shù)測定。咨詢，我們將竭誠為你服務(wù)！
Anti-phospho-CDKN2A(Ser8),磷酸化抑癌基因p16抗體科研產(chǎn)品介紹：
This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene.
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Anti-phospho-CDKN2A(Ser8),磷酸化抑癌基因p16抗體科研產(chǎn)品詳情：
產(chǎn)品編號：HRK-5255R
產(chǎn)品規(guī)格: 0.1ml/0.2ml
產(chǎn)品別名：p-CDKN2A/p16-INK4a(Ser8); p-p16-INK4a(Ser8); cyclin-dependent kinase inhibitor 2A;CDK4I; p16-INK4; p16-INK4a; cyclin-dependent kinase 4 inhibitor A; cyclin-dependent kinase inhibitor 2A, isoform 1; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cell cycle inhibitor; cyclin-dependent kinase inhibitor 2a p16Ink4a; cell cycle regulator; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 2; Cdkn2a; Arf; INK4A; MTS1; p16; p16Cdkn2a; p19ARF; CD2A1_HUMAN
產(chǎn)品價格：詢價(電詢或客服)
產(chǎn)品用途：科研實驗
貯 存： 貯存于-20℃.
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