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華瑞科研網(wǎng)-ELISA試劑盒
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華瑞科研網(wǎng)-ELISA試劑盒
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所 在 地上海市
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更新時間：2018-05-18 15:34:51瀏覽次數(shù)：544次
聯(lián)系我時，請告知來自 智慧城市網(wǎng)“Anti-Cyclin E抗體,周期素E抗體科研"我公司擁有*的細(xì)胞服務(wù)技術(shù)，*的儀器設(shè)備和專業(yè)的ELISA檢測試劑盒、生物索標(biāo)記、熒光索標(biāo)記、酶標(biāo)記等，廣泛用于多種分析研究與技術(shù)測定。咨詢，我們將竭誠為你服務(wù)！
Anti-Cyclin E抗體,周期素E抗體科研產(chǎn)品介紹：
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available. Transcript Variant: This variant (1) contains a different 5' end region, which includes an upstream in-frame translation start codon, when compared to variant 2. The encoded protein has a 15 aa longer N-terminus, as compared to isoform 2.
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產(chǎn)品詳情：
產(chǎn)品編號：HRK-0573R
產(chǎn)品規(guī)格: 0.1ml/0.2ml
產(chǎn)品別名：CCNE 1; CCNE; CCNE1; Cyclin E1; Cyclin Es; Cyclin Et; CyclinE; G1/S specific cyclin E; G1/S-specific cyclin-E1; CCNE1_HUMAN
產(chǎn)品價(jià)格：詢價(jià)(電詢或客服)
產(chǎn)品用途：科研實(shí)驗(yàn)
貯 存： 貯存于-20℃.
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