Anti-phospho-B-Raf(Ser446),磷酸化B-Raf抗體科研產(chǎn)品介紹:
The Raf kinases are important intermediates in signal transduction. Raf protein family members, including A Raf and B Raf, have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK (also known as MAP kinase kinase). Defects in BRAF are involved in a wide range of cancers. B-Raf is a serine/threonine protein kinase that acts as a signal transducer from membrane-associated receptors to nuclear transcription factors. 1 BRAF is important for the regulation of cell proliferation and determination of cell fate during embryogenesis. BRAF acts downstream of Ras and upstream of MEK in the Ras-Raf-MEK-ERK signal transduction pathway, which is a conserved RAS-activated protein kinase cascade that regulates cell growth, proliferation, and differentiation in response to growth factors, cytokines, and hormones.

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Anti-phospho-B-Raf(Ser446),磷酸化B-Raf抗體科研產(chǎn)品詳情:
產(chǎn)品編號:HRK-5232R
產(chǎn)品規(guī)格: 0.1ml/0.2ml
產(chǎn)品別名:B Raf (phospho S446); p-B Raf (phospho S446); 94 kDa B raf protein; B raf 1; B Raf proto oncogene serine threonine protein kinase; BRAF 1; Braf; BRAF1; cRmil; MGC126806; MGC138284; Murine sarcoma viral (v-raf) oncogene homolog B1; Murine sarcoma viral v raf oncogene homolog B1; p94; RAFB 1; RAFB1; v raf murine sarcoma viral oncogene homolog B1; FLJ95109
產(chǎn)品價格:詢價(電詢或客服)
產(chǎn)品用途:科研實(shí)驗(yàn)
貯 存: 貯存于-20℃.
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