Anti-ADM抗體,腎上腺髓質(zhì)素抗體Background: Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.
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Anti-ADM抗體,腎上腺髓質(zhì)素抗體Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Specificity :
Anti-ADM/AM is a rabbit polyclonal antibody unconjugated
specific for ADM/AM of rat,mo，hu
use for western blotting,elisa,immunoprecipitation and immunohistochemistry
Protein G affinity chromatography purification, purity :>95%
Isotype: IgG
mol wt: 20kDa
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